Distribution of monkey esophagus antigens reactive with IgA-class antibodies in the sera of dermatitis herpetiformis patients |
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| Authors: | V. Kumar E. H. Beutner T. P. Chorzelski |
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| Affiliation: | (1) Department of Microbiology, State Universityof New York at Buffalo, 14214, NY, USA;(2) Department of Dermatology, State University of New York at Buffalo, 14214, NY, USA;(3) IF Testing Service, 14223 Buffalo, NY, USA;(4) Department of Dermatology, Warsaw Academy of Medicine, Warsaw, Poland |
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| Abstract: | Summary Antibodies of IgA class reactive to the lining of the smooth muscle bundles, i.e., endomysium (EmA), are present in the sera of patients with dermatitis herpetiformis and coeliac disease. These antibodies can be detected on monkey esophagus, a substrate of choice for pemphigus and pemphigoid antibodies. The amount of antigen reactive with IgA-EmA is greatest in the lower portion of the esophagus and decreases towards the uppermost part.This work was supported in part by the Summerhill Foundation and by the Polish Academy of Medicine |
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| Keywords: | Monkey esophagus Dermatitis herpetiformis Antiendomysium antibodies Coeliac disease Autoantibodies |
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