| 三硝基甲苯对机体红细胞免疫功能影响的探讨 |
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| 引用本文： | 王刚垛,林瑞存,张宝义,高玉民. 三硝基甲苯对机体红细胞免疫功能影响的探讨[J]. 山东大学学报(医学版), 1993, 0(1) |
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| 作者姓名： | 王刚垛 林瑞存 张宝义 高玉民 |
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| 作者单位： | 山东省劳动卫生职业病防治研究所，山东省劳动卫生职业病防治研究所，山东省劳动卫生职业病防治研究所，山东省医学科学院基础医学研究所 |
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| 摘 要： | 检测了TNT接触者红细胞免疫功能及红细胞免疫调节因子的变化。结果发现,TNT接触者红细胞C_3b受体花环形成率显著下降,红细胞免疫复合物花环形成年显著升高,肝大者上述变化更为显著。血清中红细胞免疫调节因子无明显变化,而肝大组红细胞免疫抑制因子明显增高,红细胞免疫促进因子则明显降低。说明TNT按触者红细胞免疫功能低下,为TNT中毒的免疫机理研究提供了新的依据。
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| 关 键 词： | 三硝基甲苯 红细胞 免疫测定 |
RESEARCH OF THE EFFECTS OF TRINITROTOLUENE(TNT)ON HUMAN RBC IMMUNE FUNCTION |
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| Wang Gangduo,et al Shandong Institute of Labour Health and Occupational Disease. RESEARCH OF THE EFFECTS OF TRINITROTOLUENE(TNT)ON HUMAN RBC IMMUNE FUNCTION[J]. Journal of Shandong University:Health Sciences, 1993, 0(1) |
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| Authors: | Wang Gangduo et al Shandong Institute of Labour Health Occupational Disease |
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| Abstract: | The variations of RBC immune function and RBC immuneregutory factors were detected in workers exposed to TNT,The results showedthat by contrast with control group,RRCF rat in workers exposed to TNTdecreased,RRSF rat remarkably increased.And in hepatomegaly workers,thechanges were more significant.The changes of RBC immune regutory factorin serum of workers exposed to TNT had no statistical significance comparedwith control group,and RBC immune adherence enhance inhibitory factorswere remarkably increased,RBC immune adherence enhance factors weresignificantly decreased in serum of hepatomegaly workers,So RBC immunefunction of workers exposed to TNT was lower.The study provided newevidences for immunity mechanism study of TNT poisoning. |
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| Keywords: | Trinitrotoluene Erythrocytes Immunoassay |
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