慢性肝病患者医院感染危险因素分析

目的 了解慢性肝病患者医院感染特点及其危险因素。方法 对2000年1月～2002年12月在某院住院的1797例慢性活动性肝炎重度、慢性重型肝炎及肝硬化患者医院感染情况进行回顾性调查。结果 医院感染率为6．34％，感染组病死率为29．82％，高于非感染组(10．99％)；腹腔感染占首位，病原菌以革兰阴性杆菌为主；医院感染的发生与高胆红素和低蛋白血症密切相关。结论 慢性重型肝炎和肝硬化活动期肝病患者医院感染率较高；医院感染可影响预后。

Analysis of the risk factors for nosocomial infection in patients with chronic hepatic diseases

Objective To evaluate the feature and risk factors of nosocomial infection (NI) in patients with chronic hepatic diseases. Methods Retrospective investigation was made on 1 797 patients with chronic active hepatitis, chronic severe hepatitis and hepatic cirrhosis. Results NI rate was 6.34%, the mortality of patients with infection ( 29.82%) was higher than that without infection ( 10.99%), the main infection site was abdominal cavity, most pathogens were Gram-negative bacilli, infection was likely to occur if patients developed hyperbilirubinemia or hypoproteinemia. Conclusion The NI rate is higher in patients with chronic severe hepatitis and hepatic cirrhosis; infection can affect the prognosis.