Development of a new immunoassay for the accurate determination of anti-infliximab antibodies in inflammatory bowel disease期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Development of a new immunoassay for the accurate determination of anti-infliximab antibodies in inflammatory bowel disease

Authors:	Hirotsugu Imaeda Akira Andoh Yoshihide Fujiyama

Affiliation:	(1) Department of Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu 520-2192, Japan;(2) Division of Mucosal Immunology, Graduate School, Shiga University of Medical Science, Seta-Tukinowa, Otsu 520-2192, Japan;

Abstract:	Background The formation of antibodies to infliximab (ATIs) is closely associated with the loss of response to infliximab in patients with inflammatory bowel disease (IBD). We evaluated the clinical utility of a novel method to measure serum ATI levels in the presence of infliximab.

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