Localized malignant peritoneal mesothelioma containing rhabdoid cells |
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Authors: | Susumu Matsukuma Shinsuke Alda Yoshinobu Hata Yoshiaki Suglura Seiichi Tamai |
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Affiliation: | Department of Laboratory Medicine, National Defense Medical College, Tokorozawa, Tokyo, Japan;Second Department of Surgery, National Defense Medical College, Tokorozawa, Tokyo, Japan;Department of Research and Laboratory, Japan Self Defense Force Central Hospital, Tokyo, Japan |
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Abstract: | A case Is presented of localized malignant peritoneal mesothelioma appearing as a liver neoplasm. The patient underwent tumor resection but developed a recurrent growth and died 10 months after the Initial surgery. The primary tumor showed sarcomatous features with rhabdoid cells. Examination revealed the presence of hyaluronic acid, co-Immunoreactivlty for cytokeratln epithelial membrane antigen and vlmentln, cellular contacts with small desmosomes, and intracytoplasmic lumina. These findings supported the mesothelial nature of this tumor. The recurrent tumor was composed of predominantly tubulopaplllary proliferation. It was concluded that the present tumor was a localized malignant mesothelioma of a blphasic type showing a predominantly sarcomatous component in the primary tumor. |
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Keywords: | immunohistochemistry localized mesothelioma malignant peritoneal mesothelioma rhabdoid cell ultrastructure |
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