| Abstract: | The location of chlorine ions in the parietal cells of the mouse and rat gastric mucosa was studied by electron-histochemical and autoradiographic methods together with the direct method of detection of radioactive isotopes in tissue. On the basis of the results a scheme of specific transport of chlorine ions is proposed and envisages the transposition of individual layers of the cell membrane, double folds of the basal plasmalemma, tubulovesicles, and intracellular tubules. This interconversion takes place in the course of the secretory cycle of the cell and is directly dependent on it. A nonspecific pathway for the transport of the total chlorides of the gastric juice across intercellular spaces is postulated.Laboratory of Pathomorphology, Institute of Nutrition, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR N. A. Kraevskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 7, pp. 29–32, July, 1977. |
