| 参附注射液对压力后负荷性急性心衰大鼠血流动力学的影响 |
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| 引用本文： | 黄琼,指导：徐伟建.参附注射液对压力后负荷性急性心衰大鼠血流动力学的影响[J].实用中西医结合临床,2005,5(2):6-7. |
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| 作者姓名： | 黄琼 指导：徐伟建 |
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| 作者单位： | 1. 湖北中医学院硕士研究生,武汉,430061
2. 湖北省中医院,武汉,430061 |
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| 摘 要： | 目的:研究参附注射液对急性心衰大鼠血流动力学的影响。方法:用腹主动脉缩窄造成急性心衰大鼠模型,观察参附注射液对急性心衰大鼠血流动力学各指标的影响。结果:参附注射液与西地兰、多巴酚丁胺比较,有同等的正性肌力作用(P>0.05),与模型组比较使LVSP、+dp/dtmax升高(P<0.01),但与西地兰组、多巴酚丁胺比较,参附注射液能同时降低LVEDP(P<0.01)。结论:参附注射液与西地兰、多巴酚丁胺同等的正性肌力作用,但它同时能降低左室舒张末内压,治疗舒张性心力衰竭。
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| 关 键 词： | 参附注射液 急性心力衰竭 血流动力学 实验研究 |
| 文章编号： | 1671-4040(2005)02-0006-02 |
| 修稿时间： | 2004年10月25 |
Hemodynamics Effects of Shenfu Parenteral Solution on Acute Congestiue Heart Failure Rat |
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| Huang Qiong,Xu Wei-jian.Hemodynamics Effects of Shenfu Parenteral Solution on Acute Congestiue Heart Failure Rat[J].Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine,2005,5(2):6-7. |
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| Authors: | Huang Qiong Xu Wei-jian |
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| Abstract: | objective:to investigate the hemodynamics effect of ShenFu parenteral solution on acute congestive heart failure rat. Methods: to use coarctation of abdomial aorta to result in acute congestive heart failure rat. To observe the hemodynamics marker of acute congestive heart failure rat. Result:to compare ShenFu parenteral solution with cedilanid and dobutamine, they have tantamount positive action (P >0.05). To compare ShenFu pareteral solution bundle with model bundle, ShenFu parenteral solution can make LVSP?+dp/dtmax set-up (P <0.01), but to compare ShenFu parenteral solution with cedilanid and dobutamine , ShenFu parenteral solution can decrease LVEDP (P <0.01). Conclusion: to compare ShenFu parenteral solution with cedilanid and dobutamine. ShenFu parenteral solution have tantamount positive action , but it can decrease LVEDP and treat relax heart failure. |
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| Keywords: | ShenFu parenteral solution acute congestive heart failure hemodynamics experiment investigation |
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