百合知母胶囊的质量标准研究

 目的 建立百合知母胶囊的质量标准。方法 采用薄层色谱法（thin layer chromatography，TLC）对百合、知母进行定性鉴别；采用高效液相色谱法（high performance liquid chromatography，HPLC）测定制剂中芒果苷含量。结果 应用薄层色谱法鉴别知母具有专属性，而该法鉴别百合不具有专属性；芒果苷在 0.0674～1.3480 μg范围内呈良好的线性关系，相关系数r=0.9998；检测下限为0.0674 μg，芒果苷的平均回收率为（98.890±0.497）％，RSD=0.50%。结论 本方法操作简便，结果准确，重复性好，可用于该制剂的质量控制。

Quality standard of Bulbus Lilii-rhizoma anemarrhenae capsule

Objective To establish quality standard of Bulbus Lilii-Rhizoma Anemarrhenae capsules.Methods The Bulbus Lilii and Rhizoma Anemarrhenae were identifed in the capsules by TLC.HPLC was adopted to determine the content of mangiferin.Results The chief medical materials Rhizoma Anemarrhenae in the capsule and the corresponding reference substances showed the identical discrimination reactions,but Bulbus Lilii did not so.The mangiferin curve showed good linearity over the range of 0.0674-1.348 μg,r=0.9998,and the lower detection limit was 0.0674 μg.The average recovery was 98.89±0.497%,RSD=0.50%.Conclusion The method is sensitive in qualitative reaction,specific in TLC identification,accurate in HPLC quantitation,and repentable.The established standard is applicable to the quality control of Bulbus Lilii-rhizoma anemarrhenae capsules.