每日短时血液透析对糖尿病肾病重度浮肿患者的意义

目的]研究每日短时血液透析(daily hemodialysis,DHD)在糖尿病肾病重度浮肿患者中的应用.方法]选择2006年1月-2010年6月在我科住院的32例糖尿病肾病(diabetic nephropathy,DN)合并重度浮肿患者,随机分为A、B两组,每组16例,A组采用DHD加DN常规药物治疗,每日行血液透析2.5～4h,连续5～14d;B组单纯应用DN常规药物治疗.观察两组尿蛋白、血浆白蛋白、肾功能、心脏指数、浮肿等情况变化.结果]A、B两组治疗后尿蛋白均减少,血浆白蛋白上升,肾功能均得到不同程度改善.A组患者浮肿完全消退,较B组临床症状改善明显(P＜0.05).结论]DHD对DN合并重度浮肿患者有明显疗效.

Clinical application of short daily hemodialysis in case of diabetic nephropathy with severe edema

【Objective】Objective To study the clinical application of short daily hemodialysis in case of diabetic nephropathy with severe edema.【Methods】 32 cases were divided into two groups randomly,Group A used DHD and conventional drugs,Group B received drugs only.Group A was treated by hemodialysis 2.5 to 4 hours daily,continued for 5 to 14 days.The urinary protein,plasma proteins,renal functions were observed in Group A and Group B.【Results】Both two groups after treatment of urinary protein were reduced,plasma albumin rises,renal function were improved in different degree.A group all patients with edema were dissipated,in A group than in B group,the clinical symptoms improved significantly(P < 0.05).【Conclusion】 DHD has remarkable effect on diabetic nephropathy with severe edema.