组织速度成像技术对心脏再同步化治疗慢性心衰的疗效观察

目的]应用常规超声心动图、组织速度成像技术对慢性心力衰竭患者心脏再同步化治疗(CardiacResynchronization Therapy,CRT)疗效的观察.方法]观察19例慢性心衰患者CRT术后1周、3个月、6个月左心室舒张末径、左房前后径、左室射血分数及左室机械同步性指标的变化.结果]与术前相比,术后6个月左室舒张内径降低(83±7.60 mm)比(65.00±7.85mm),(P＜0.05)],与术前相比,术后1周,3个月左室舒张内径无明显差异(83±7.60mm)比(71.64±6.83mm)、(66.88±6.73 mm),(P＞0.05)].与术前相比,术后1周、3个月、6个月左房前后径无明显差异(51.38±7.30m m)比(46.64±7.04mm)、(46.22±9.48mm)、(51.00±8.12 mm),(P＞0.05)].与术前相比,术后6个月左室射血分数升高(28.72±4.5％)比(33.75±5.54％),(P＜0.05)],与术前相比,术后1周、3个月左室射血分数无明显差异(28.72±4.5％)比(31.06±5.04％)、(32.40±3.80％),(P＞0.05)].与术前相比,术后6个月左室机械同步性指标TS-12SD降低(33.30±17.49ms)比(22.36±11.78ms),(P＜0.05)],与术前相比,术后1周,3个月左室机械同步性指标TS-12SD无明显差异(33.30±17.49ms)比(35.28±12.36ms)、(29.75±12.80ms),(P＞0.05)].结论]组织速度成像技术显示慢性心力衰竭患者心脏再同步化治疗术后6个月,疗效明显改善.

Evaluation of cardiac resynchronization therapy in the patient of chronic heart failure by quantitative tissue velocity imaging

Objective] To apply usual echocardiography and quantitative tissue velocity imaging to evaluate the effect of resynchronization therapy（CRT） in the patients of chronic heart failure. Methods] There were 19 patients, the diameter of left ventricular diastolic（LVDD）, the diameter of left atrium （LAD）, the left ventricular ejection fraction （LVEF） and standard deviation of the time to peak systolic velocity in 12 segments ventricular wall were measured at one week before CRT operation, one week ,three months, six months and one year after CRT by usual echocardiography and quantitative tissue velocity imaging. Results] LVDD decreased 6 months after therapy（83 ± 7.60 mm）VS （65.00 ± 7.85 ram）, （P 〈 0.05）], there were no difference before and 1 week, 3months after therapy（83 ± 7.60 mm）VS （71.64 ± 6.83 mm）, （66.88 ± 6.73 mm）,（P 〉 0.05）]. LAD was no difference before and 1 week, 3 months, 6 months after therapy（51.38 ± 7.30 mm）VS （46.64 ± 7.04mm）, （46.22 ± 9.48mm）, （51.00 ± 8.12 mm）, （P 〉 0.05）]. LVEF increased 6 months after therapy（28.72 ± 4.5 %）VS （33.75 ± 5.54%）, （P 〈 0.05 ）], there were no difference before and 1 week, 3months after therapy （28.72 ± 4.5 %）VS （31.06 ± 5.04%）, （32.40 ± 3.80%）, （P 〉 0.05）]. TS-12SD decreased 6 months after therapy（33.30 ± 17.49ms）VS 22.36 ± ll.78ms）, （P 〈 0.05）], there were no difference before and 1 week, 3months after therapy（33.30 ± 17.49ms）VS （35.28 ± 12.36 ms）, （29.75 ± 12.80ms）, （P 〉 0.05）]. Conclusion ] Quantitative tissue velocity imaging can quantitative assess the effect of CRT, the effect of CRT in the patients of chronic heart failure was obvious after six months.