白叶莓根部化学成分的研究

目的 研究蔷薇科悬钩子屑药用植物白叶莓Rubus innominatus根部的化学成分。方法用甲醇室温浸提后以乙酸乙酯萃取，萃取物通过多次正相和反相硅胶柱层析分离纯化，并采用NMR，MS等波谱方法及与标准品对照TLC鉴定化学结构，抗菌活性用杯碟法测定。结果 共分离鉴定出10个三萜酸和2个甾体类化合物，抗菌试验表明乙酸乙酯萃取物和一些三萜酸具有一定的抗菌活性。结论 这些成分均为首次从该属植物中分离得到。

Studies on chemical constituents from root of Rubus innominatus

Object To study the chemical constituents from the root of Rubus innominatus S. Moore (Rosaceae). Methods Twelve compounds were isolated from the methanol extract by repeated column chromatography over normal and reversed phase silica gels. Their structures were identified by analysis of their spectral data and comparing TLC with authentic samples. Results Ten triterpenic acids and two steroids were isolated and identified. The antibacterial test indicated some triterpenic acids had antibacterial activity. Conclusion All compounds were obtained from the plants of Rubus L. for the first time.