The treatment of ANCA-associated rapidly-progressive glomerulonephritis and Goodpasture syndrome with therapeutic apheresis |
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Authors: | Suheyla Apaydin |
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Affiliation: | University of Health Sciences, Medical Faculty, Internal Medicine, Bakirkoy Dr. Sadi Konuk Training and Research Center, Nephrology Department, Istanbul, Turkey |
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Abstract: | Therapeutic plasma aphresis (plasmapheresis) is one form of treatment that is frequently used in practice of Nephrology. Plasmapheresis is the most important part of the therapies for Goodpasture's syndrome and anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis which are causes of rapidly progressive glomerulonephritis. The reason why the effectiveness of plasmapheresis therapy cannot be clearly demonstrated in renal involvement in these diseases is that it does not appear to be possible to recruit an adequate number of patients and plasmapheresis is not effective in advanced disease if early treatment is not initiated. |
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Keywords: | Plasmapheresis Goodpasture’s Syndrome ANCA Associated Vasculitis Treatment |
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