| 康复训练对脑血栓形成患者血浆组织型纤溶酶原激活物及抑制物活性的影响 |
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| 引用本文： | 沈志祥,周士枋,励建安,高润.康复训练对脑血栓形成患者血浆组织型纤溶酶原激活物及抑制物活性的影响[J].中国康复医学杂志,1996(6). |
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| 作者姓名： | 沈志祥 周士枋 励建安 高润 |
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| 作者单位： | 江苏省淮阴市第二人民医院康复医学科，江苏省人民医院，南京脑科医院 |
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| 摘 要： | 以４０例亚急性期、恢复早期脑血栓形成偏瘫患者为研究对象，随机分成康复治疗组和对照组，观察分析康复训练后即刻及３周后纤溶活性的变化。２０例健康老年人作为正常对照。结果为：康复治疗后即刻、康复后３周与康复前相比，组织型纤溶酶原激活物活性分别提高３０％和１２．６％，组织型纤溶酶原抑制物与激活物比值降低，纤溶活性增高（Ｐ＜０．０１），并高于对照组（Ｐ＜０．０１）。康复训练可部分逆转脑血栓形成患者组织型纤溶酶原激活物及抑制物的异常改变，提高纤溶活性。
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| 关 键 词： | 脑血栓形成 组织型纤溶酶原激活物 康复训练 |
Effects of rehabilitation training on activity of tissue-type
plasminogen activator,plasminogen activator inhibitor in cerebral
thrombosis |
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| Abstract: | The goal of this study was to observe effects of rehabilitation
training on fibrinolytic activity in hemiplegic patients with
cerebral thrombosis.Forty cerebral thrombosis patients in subacute or
early recovery phase were randomly divided into rehabilitation and
control groups. Twenty health elderly's people were taken as the
control group.Results:Comparing data of an immediate rehabilitation
treatment and a delay for three week before rehabilitation to the
baseline,the tissue-type plasminogen activator(t-PA)activity
increased 30%and 12.6% respectively,plasminogen activator
inhibitor(PAI)ratio decreased.and the fibrinolytic activity improved
significantly (P<0.01).The above parameters were higher in
rehabilitation group than in control group,except PAI/t-PA ratio.
Conclusion:The rehabilitation training might partly reverse the blood
abnormality of t-PA and PAI activity,and improve fibrinolytic
activity .Author's address:(Department of Rehabilitation,Huaiyin
Second Hospital,Jiangsu,223002) |
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| Keywords: | Cerebral thrombosis Plasminogen activator of tissue-type Rehabilitation training |
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