阻塞性睡眠呼吸暂停低通气综合征与高血压的关系探讨

目的探讨阻塞性睡眠呼吸暂停低通气综合征（OSAHS）与高血压的关系。方法将62例经多导睡眠图监测仪监测证实为OSAHS的患者分为伴高血压（34例）和无高血压（28例）2组,比较2组患者的呼吸暂停低通气指数、最低血氧饱和度、呼吸暂停最长时间、觉醒指数,同时测量2组患者睡前、醒时血压。结果 OSAHS伴高血压组与无高血压组比较,呼吸暂停低通气指数〔（65.2±20.1）vs（36.7±18.4）次/h〕、呼吸暂停最长时间〔（58.4±10.7）vs（46.3±12.5）s〕、觉醒指数〔（41.2±13.6）vs（20.4±11.7）次/h〕差异均有统计学意义（P均〈0.05）。伴高血压组最低血氧饱和度低于无高血压组〔（67±11）%vs（75±10）%〕（P〈0.05）。OSAHS伴高血压组的睡前和醒时血压均明显高于无高血压组（P均〈0.05）,且OSAHS伴高血压组醒时血压明显高于睡前血压（P〈0.05）;而OSAHS无高血压组的醒时血压与睡前血压相比差异无统计学意义（P〉0.05）。结论 OSAHS与高血压关系密切,OSAHS可能是引起或加重高血压的病因之一

The relationship between obstructive sleep apnea hypopnea syndrome and hypertension

Objective To investigate the relationship between obstructive sleep apnea hypopnea syndrome （OSAHS） and hypertension. Methods A total of 62 patients with OSAHS confirmed by monitoring of polysomnography monitor were divided into with hypertension group and without hypertension group.The apnea hypoventilation index（AHI）,lowest oxygen saturation（SpO2）,longest apnea time（LAT）and arousal index（AI） were compared in two groups,and blood pressure before going to bed and awake blood pressure were measured also in two groups. Results AHI,LAT and AI in OSAHS with hypertension group were significantly higher than those in OSAHS without hypertension group〔（65〈2±20〈1） vs （36〈7±18〈4）times/h,（58〈4±10〈7） vs （46〈3±12〈5）s,（41〈2±13〈6） vs （20〈4±11〈7） times/h,respectively,all P〈0〈05〕,and the lowest SpO2 in OSAHS with hypertension group was significantly lower than that in OSAHS without hypertension group 〔（67±11）% vs（75±10）%,P〈0〈05〕.The blood pressure before bed and upon awakening in OSAHS with hypertension group were significantly higher than those in OSAHS without hypertension group （all P〈0〈05）.The blood pressure upon awakening was significantly higher than the blood pressure before bed in OSAHS with hypertension group（P〈0〈05）,while the blood pressure before bed and upon awakening had no significant difference in OSAHS without hypertension group（P〉0〈05）.Conclusions OSAHS and hypertension have close correlation,and OSAHS might be one of the causes which induce correlation or exacerbate hypertension