健康相关生命质量中医体质因素分析:健康与慢病不同亚组的分层分析

[目的]分析健康人群与慢病人群健康相关生命质量(HRQoL)与中医体质因素之间的关系,并比较两组之间的异同。[方法]将一般人群中医体质和健康状况调查数据库中的21164例纳入研究,以SF-36量表评价HRQoL,采用中医体质量表与判别分析进行中医体质判断,健康人群与慢病人群HRQoL与中医体质的关系采用Logistic回归进行分析。[结果]平和质HRQoL得分最高,生理领域气虚质HRQoL得分最低,心理领域气郁质HRQoL得分最低。健康人群的生理领域HRQoL减损危险度(OR值)较高的体质是血瘀质、痰湿质、气虚质,健康人群的心理领域及慢病人群的生理和心理领域则是气郁质、痰湿质、气虚质。[结论]健康人群和慢病人群中医体质与HRQoL之间的关系相似。

Factor analysis between health-related quality of life and traditional Chinese medicine constitution: lamination analysis on healthy adults and patients with chronic diseases in different subgroups

[Objective] To investigate the relationship between health-related quality of life (HRQoL) and traditional Chinese medicine (TCM) constitution in healthy population and patients with chronic diseases. [Methods] A total of 21 164 subjects were included in this study. The HRQoL was evaluated by SF-36; the TCM constitution was evaluated by the Constitution in Chinese Medicine Questionnaire and classified by the Discriminant Analysis. Multiple Logistic Regression analysis was used to explore the relations between TCM constitution and HRQoL. [Results] The HRQoL score of gentleness type was the highest in both physical component summary (PCS) and mental component summary (MCS). The HRQoL score of qi-deficiency type was the lowest in PCS and that of qi-depression type was the lowest in MCS. The three constitutional types with the largest odds rations (ORs) in PCS of healthy subjects were blood-stasis type, phlegm-wetness type, and qi-deficiency type, while in MCS of healthy subjects and in both PCS and MCS of patients were qi-depression type, phlegm-wetness type and qi-deficiency type. [Conclusion] The correlation of TCM constitution and HRQoL was similar between healthy adults and patients with chronic diseases.