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CA-50、CEA检测鉴别良恶性胸水价值探讨
引用本文:郝青林,余丽丽,赵芝焕,李庆云,张力燕,陈菊春.CA-50、CEA检测鉴别良恶性胸水价值探讨[J].肿瘤基础与临床,1999(6).
作者姓名:郝青林  余丽丽  赵芝焕  李庆云  张力燕  陈菊春
作者单位:昆明医学院一附院呼吸内科(郝青林,赵芝焕,张力燕,陈菊春),昆明医学院一附院核医学科(余丽丽,李庆云)
摘    要:目的 为寻找简便有效的方法对良恶性胸水进行鉴别诊断。方法 采用放射免疫分析技术对健康对照组30 例、已确诊的恶性胸水组15 例、良性胸水组33 例血清及胸水进行CA-50、CEA平行对照检测。结果 恶性胸水组血清及胸水CA- 50、CEA水平显著高于良性胸水组。结论 提示对胸水进行CA- 50 、CEA检测有利于良恶性胸水鉴别诊断,且CA- 50 与CEA联合检测可提高恶性胸水诊断阳性率。

关 键 词:肿瘤相关抗原  CA-50  CEA  胸腔积液

A Study on the CA-50,CEA Radioimmunoassay for the Differentiation of Bening and Malignant Hydrothorax
Hao Qinglin,Yu Lili,Zhao Zhihuan,et al.A Study on the CA-50,CEA Radioimmunoassay for the Differentiation of Bening and Malignant Hydrothorax[J].journal of basic and clinical oncology,1999(6).
Authors:Hao Qinglin  Yu Lili  Zhao Zhihuan  
Institution:Hao Qinglin,Yu Lili,Zhao Zhihuan,et al Department of Respiratory Disease,The First Affiliated Hospital of Kunming Medical College,Kunming 650032 [
Abstract:Objective To search an easy and effective method for the differential diagnosis between benign and malignant hyolrothorax.Methods The radioimmunoassay technique was used.The CA-50 level and CEA level of serum and hydrothorax were determined in 15 patients with malignant hydrothorax and in 33 patients with benign hydrothorax,and in 30 healthy persons as the control.Resulyts The results showed that the CA-50 level and CEA level of serum and hydrothorax in malignant hydrothorax were significant higher than those in bening hydrothorax ( P <0.01).Conclusions It suggested that the hydrothorax CA-50 and CEA determination be effective for the differential diagnosis between bening and malignant hydrothoraxes. The positive diagnostic rate of malignant hydrothorax would be increased when the combined determination of CA-50 and CEA was used.
Keywords:tumor associated antigen  CA-50  CEA  pleural effusion
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