中西医结合辩证治疗特发性全葡萄膜炎的疗效

目的：探讨中西医结合辩证治疗特发性全葡萄膜炎的临床疗效。

方法：将47例69眼特发性全葡萄膜炎患者随机分为治疗组和对照组两组，对照组24例33眼用全身及局部糖皮质激素和局部散瞳药物治疗； 治疗组23例36眼联合中医辨证治疗，随访12～36mo，分别记录患者治疗前后的视力、治疗效果、并发症及激素副作用的发生。

结果：两组治疗后视力均有提高，但治疗组优于对照组； 治疗组较对照组的有效率及治愈率明显提高； 治疗组并发性白内障、继发性青光眼的发生率较对照组明显降低； 治疗组较对照组中枢兴奋症状、高血压、向心性肥胖的激素副作用明显改善(P<0.05)。

结论：中西医结合辩证治疗特发性全葡萄膜炎比单纯西医治疗有更好的疗效，并且能更好的减轻激素长期应用的副作用，值得在临床推广。

Clinical observation on treating idiopathic panuveitis with integrated traditional Chinese and Western medicine

AIM: To explore the clinical therapeutic effect of the integrated traditional Chinese and Western medicine treatment of idiopathic panuveitis.

METHODS: Totally 47 patients(69 eyes)with the idiopathic panuveitis were included in this study, which were randomly divided into control group and treatment group. Twenty-four cases(33 eyes)with the method of Western medicine-glucocorticoid and mydriatic were in control group, while 23 cases(36 eyes)with integrated traditional Chinese and Western medicine were in treatment group. Those patients were followed up 12-36mo, the vision before and after treatment, the therapeutic effects, the complications and the side effects of glucocorticoid were recorded.

RESULTS: Both of two groups' vision after treatment were improved, but the vision of treatment group was better than the control group. The effective rate and the cure rate of the treatment group were increased significantly. Of all of the complications, the incidence rate of complicated cataract and secondary glaucoma of the treatment group were reduced significantly. Of all of the side effects of glucocorticoid, the central excitation, hypertension and central obesity of the treatment group were reduced significantly(P<0.05).

CONCLUSION: Dialectical therapy of integrated traditional Chinese and Western medicine has better therapeutic effect than simple Western medicine treatment of idiopathic panuveitis, and could better reduce the side effect of glucocorticoid long-term use. It is worthy applying in clinical practice.