| KISS-1在子宫内膜异位症患者异位内膜中的表达及意义 |
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| 引用本文： | 彭来勤,廖瑞平,张兰英,黄凤英,陈江涛. KISS-1在子宫内膜异位症患者异位内膜中的表达及意义[J]. 中国基层医药, 2008, 15(6) |
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| 作者姓名： | 彭来勤 廖瑞平 张兰英 黄凤英 陈江涛 |
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| 作者单位： | 惠州市中心人民医院妇产科,广东省惠州,516001 |
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| 摘 要： | 目的 了解KISS-1在正常子宫内膜及子宫内膜异位症患者异位内膜组织中的表达关系.方法 采用免疫组织化学EliVision plus技术,检测46例患者异位子宫内膜组织,55例正常子宫内膜组织中KISS-1的表达情况,对两组间表达情况进行比较.结果 KISS-1在子宫内膜异位症患者异位内膜及正常子宫内膜组织中阳性表达率分别为30.43%和63.64%,差异有统计学意义(P<0.01,P<0.05).结论 KISS-1在子宫内膜异位症中的表达减弱可能与内异症的发病有关.
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| 关 键 词： | 子宫内膜异位症 基因,KISS-1 免疫组织化学 |
Expression and significance of KISS-1 in ectopic endometrium in patients with endometriosis |
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| PENG Lai-qin,LIAO Rui-ping,ZHANG Lan-ying,HUANG Feng-ying,CHEN Jiang-tao. Expression and significance of KISS-1 in ectopic endometrium in patients with endometriosis[J]. Chinese Journal of Primary Medicine and Pharmacy, 2008, 15(6) |
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| Authors: | PENG Lai-qin LIAO Rui-ping ZHANG Lan-ying HUANG Feng-ying CHEN Jiang-tao |
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| Abstract: | Objective To study the expression of KISS-1 in normal endometrium and in ectopic endometri-um patients with endometriosis. Methods The expression of KISS-1 in 55 cases of normal endometrium as well in 46 cases of ectopie endometriurn with endometriosis were detected by immunohistochemicai EliVision plus method. Results The positive expression rates of KISS-1 in ectopic endometriotic tissues and in normal endometri-urn were 30.43 % and 63.64 % respectively ,and the positive expression rates in ectopic endometriotic tissues signifi-cantly lower than those in the normal endometrium( P< 0.01, P < 0.05). Conclusion The decreased expression of KISS-1 may be related to the mechanism of endometriosis. |
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| Keywords: | Endometriosis Genes,KISS-1 Immunohistochemistry |
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