Antisperm Antibodies on the Surface of Spermatozoa before Ejaculation from Vasectomized Men

Itisknownthattherewereantispermantibodies(AsAbs)intheseraandsemenaftervasectomyorvasovasotomy"--".In1978ModeratorandModeraterlalraisedaquestionofwhetherAsAbscancoattheepididymalspermatozoaaftervasectomy,orexistonthesurfaceoftheepididymalspermatozoabeforeejaculation.Unforturnately,sofartherehasbeennoreportabouttheAsAbsonthehumanspermatozoaoftheepididymisorproximalvasdeferensaftervasectomy,becauseitisverydifficulttoobtainthehumanspermatozoabeforeejaculation(SBE).Nowthetechniqueofcannulationo…

Antisperm Antibodies on the Surface of Spermatozoa before Ejaculation from Vasectomized Men

The antisperm antibodies (AsAbs) coated on spermatoZoa of the proximal vas deferens (sperm before ejaculation, SBE) from 48 fertile men who were volunteers of vasectomy and 24 vasectomized men who asked for vasovasotomy,were determined by immunobead test (IBT) and sperm-cervical mucus contact test (SCMC). The results showed that in fertile men there were no positive samples of SBE in IBT and SCMC. In vasectomized men positive samples of SBE were found in 79.4% for IgG, 38.2% for IgA and 35.5% for SCMC. The AsAbs on SBE could be found at the time of less than one year to more than 3 years after vasectomy. The AsAbs were still found on the semen samples at 1~3months after vasovasotomy. Our results also indicated that the incidence of AsAbs on SBE from vasectomized men could not predict the levels of AsAbs on their ejaculated sperm after vasovasotomy. There was no significant correlation between the levels of AsAbs in serium before vasovasotomy and those on SBE from vasectomized men.