沙美特罗替卡松粉吸入剂联合太极拳锻炼对稳定期重度COPD患者的影响

目的 探讨沙美特罗替卡松粉吸入剂(舒利迭)联合太极拳锻炼对稳定期重度COPD患者的影响.方法 将稳定期重度COPD患者76例随机分组为观察组和对照组各38例,脱落6例,最终入组各35例.2组在常规治疗基础上,观察组给予沙美特罗替卡松粉吸入剂50 μg/500 μg吸入及太极拳锻炼.对照组只给予沙美特罗替卡松粉吸入剂50 μg/500 μg吸入.2组疗程均为6个月,并随访至少1年统计门诊及住院次数.结果 2组在肺功能、活动能力、生活质量方面均较前明显改善(P＜0.05),观察组免疫功能明显高于对照组(P＜0.05),门诊及住院次数明显低于对照组(P＜0.05).结论 沙美特罗替卡松粉吸入剂联合太极拳锻炼不仅能改善稳定期重度COPD患者的肺功能、活动能力和生活质量,还能提高患者免疫功能,减少门诊及住院次数.

Effect of seretide combined with Tai Chi on severe COPD patients in stable period

Objective To explore the effect of seretide combined with Tai Chi on severe COPD patients in stable period.Methods Seventy-six COPD cases in stable period were divided randomly into two groups,with 38 cases in the observation group and 38 in the control group.But finally only 35 cases were included in each group respectively because 6 cases fell off.Beside the regular treatment for both groups,the observation group also received inhalation of Seretide 50 μg/500 μg with the exercise of Tai Chi,while the control group received only inhalation of Seretide 50 μg/500 μg.The treatment for both groups lasted for 6 months with at least 1 year's follow-up for the frequency of their outpatient visits and inpatient admissions.Results Both groups showed significant improvement in lung function,mobility and quality of life (P ＜ 0.05) compared with their former performance,but the immune function of the observation group was higher than that of the control group and the difference was significant (P ＜0.05),and their frequency of outpatient visits and inpatient admissions was significantly lower than that of the control group (P ＜0.05).Conclusions Seretide combined with Tai Chi on severe COPD patients in stable period can not only improve their lung function,mobility and quality of life,but also raise their immune function and reduce the frequency of outpatient visits and inpatient admissions.