| 非小细胞肺癌EGFR靶向治疗的研究进展 |
| |
| 引用本文： | 孙苹苹,陈建荣.非小细胞肺癌EGFR靶向治疗的研究进展[J].国际呼吸杂志,2017,37(2). |
| |
| 作者姓名： | 孙苹苹 陈建荣 |
| |
| 作者单位： | 226001,南通大学第二附属医院呼吸科 |
| |
| 摘 要： | 肺癌是目前世界上发病率和病死率最高的癌症,其中非小细胞肺癌(NSCLC)占肺癌的85％以上.近10年来,随着对肿瘤生物学的深入研究,作为NSCLC治疗靶点的多个基因突变已被识别,其中表皮生长因子受体(EGFR)基因的突变频率最高,因此,EGFR基因的靶向治疗也逐渐成为NSCLC治疗的主力军.本文将就目前NSCLC中的EGFR基因突变及其靶向治疗药物进行简要阐述.
|
| 关 键 词： | 非小细胞肺癌 表皮生长因子受体 靶向治疗 |
Advances in EGFR-targeted therapy of non-small cell lung cancer |
| |
| Sun Pingping,Chen Jianrong.Advances in EGFR-targeted therapy of non-small cell lung cancer[J].International Journal of Respiration,2017,37(2). |
| |
| Authors: | Sun Pingping Chen Jianrong |
| |
| Abstract: | Lung cancer is currently the cancer with the highest incidence and mortality in the world.Non-small cell lung cancer accounts for more than 85 ％ of lung cancer.With a deep study of tumor biology,multiple mutations as therapeutic targets have been identified in recent ten years,wherein the frequency of epidermal growth factor receptor (EGFR) mutation is the highest.Therefore,EGFR targeted therapy of non-small cell lung cancer has become the main force.This review presents EGFR mutation and targeted therapies of non-small cell lung cancer. |
| |
| Keywords: | Non-small cell lung cancer Epidermal growth factor receptor Targeted therapy |
| 本文献已被 万方数据 等数据库收录！ |
|
