布地奈德雾化吸入对小儿支气管哮喘的临床疗效观察的Meta分析

目的 探讨雾化吸入布地奈德对小儿支气管哮喘的护理和临床疗效.方法 计算机检索中国知网、万方数据库和维普等数据库中关于布地奈德雾化吸入和常规护理用于小儿支气管哮喘疗效观察的随机对照试验,对符合纳入标准的研究进行质量评价,并采用RevMan 5.2统计软件进行Meta分析.从疗效、临床症状体征改善时间和肺活量改变等方面来评价布地奈德雾化吸入对缓解小儿支气管哮喘症状的效果.结果 共纳入11篇研究(总计1 174例).Meta分析结果显示,观察组和对照组在疗效、临床症状体征改善时间和肺活量改变等方面比较差异均有统计学意义.结论 与常规护理相比,布地奈德雾化吸入在小儿支气管哮喘的临床护理方面效果显著,能显著增加疾病治疗的效果,缩短咳嗽、喘音和哮鸣音消失的时间,同时还能增加支气管哮喘患儿的肺活量.

Meta-analysis of nursing and clinical efficacy of budesonide on children with bronchial asthma

Objective To explore the nursing and clinical efficacy of budesonide inhalation on children with bronchial asthma.Methods The computer retrieval on China CNKI;Wanfang database and VIP database was conducted for the randomized controlled trials in terms of budesonide inhalation and routine nursing to observe the curative effect of bronchial asthma on children;and the studies meeting the inclusion criteria were evaluated;and Meta analysis was performed by RevMan 5.2 statistical software.The effect of Budesonide aerosol inhalation to alleviate the symptoms of bronchial asthma on children was evaluated from the aspects of curative effect;the change of time for clinical symptoms and signs and vital capacity.Results A total of 11 studies (1 174 cases) were included in this study.Meta analysis showed that there were statistical significances in terms of differences of curative effect;the change of time for clinical symptoms and signs and vital capacity of the two groups.Conclusion Compared with the conventional nursing;budesonide inhalation was shown high effect on the clinical nursing for children with bronchial asthma;which can not only significantly increase the therapeutic effect;reduce the cough;asthma and wheezing disappearance time;but also increase the vital capacity of children with bronchial asthma.