| 红景天素抗大鼠心肌老化的超微结构体视学定量研究 |
| |
| 引用本文： | 潘力,李颖,栗振宝. 红景天素抗大鼠心肌老化的超微结构体视学定量研究[J]. 吉林大学学报(医学版), 1997, 0(3) |
| |
| 作者姓名： | 潘力 李颖 栗振宝 |
| |
| 作者单位： | 基础医学院电镜室 |
| |
| 摘 要： | 提供开发红景天抗老化作用形态学依据。利用透射电镜和体视学方法定量地计算了红景天素对老龄大鼠心肌超微结构的影响。结果显示：以心肌细胞为参照系，细胞成分增加，间质成分减少；以肌细胞为参照系，细胞核和线粒体的体密度增加，脂褐素的体密度减少；线粒体体密度／肌原纤维体密度增加；线粒体外膜比面积和线粒体内膜＋嵴比面积增加。结果提示，红景天素具有预防或延缓心肌老化作用。
|
| 关 键 词： | 红景天素 心肌老化 超微结构 体视学 |
Stereological quantitative study on ultrastructure of anti-ageing effects of Rhodosin on myocardium in rats |
| |
| Pan Li,Li Ying,Li Zhenbao. Stereological quantitative study on ultrastructure of anti-ageing effects of Rhodosin on myocardium in rats[J]. Journal of Jilin University: Med Ed, 1997, 0(3) |
| |
| Authors: | Pan Li Li Ying Li Zhenbao |
| |
| Affiliation: | Department of Electron Microscopy |
| |
| Abstract: | Using TEM and stereological method ,effects of Rhodosin on myocardical ultrastructure in ageing rats were quantitatively calculated.These results showed that ① in the reference of myocardium,volume density (V.D) of myocyte portion (Vcell) increased ,and V.D. of interstitial portion (Vinter ) decreased;②in the reference of myocyte ,V.D. of nucleus (Vun) and V.D. of mitochondria (Vmi) increased ,and V.D. of lipofusin (Vif) decreased;③V.D. of mitochondria/V.D.of myofibril (Vmf) also increased;④Specific surface (S.S) of outer membrane of mitochondria (δouter) and S.S.of inner membrane + cristae of mitochondria (δinner + c) increased.These results suggest that Rhodosin possessses effects of prolonging or preventing myocardium ageing. |
| |
| Keywords: | Rh odosin Ageing myocardium Ultrastructure Stereology |
| 本文献已被 CNKI 等数据库收录！ |
