| 大黄所致脾虚模型大鼠小肠移行性综合肌电的变化 |
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| 引用本文： | 闻集普,王建华,陈永,王伯祥.大黄所致脾虚模型大鼠小肠移行性综合肌电的变化[J].广州中医药大学学报,1992(3). |
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| 作者姓名： | 闻集普 王建华 陈永 王伯祥 |
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| 作者单位： | 广州中医学院脾胃研究室，广州中医学院脾胃研究室，湖北中医学院，湖北中医学院 |
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| 摘 要： | 采用双极银丝电极记录清醒大鼠十二指肠和空肠上段移行性综合肌电(MMC)。结果表明:以2kg/L(200％)生大黄液连续胃饲5天(4ml/只/天),造成的“脾虚”腹泻大鼠模型具有明显的脾虚证表现;与造型前比较,腹泻大鼠小肠MMCI相时程显著缩短或保持不变,而Ⅱ、Ⅲ相时程显著延长,并出现MMC周期的显著延长。提示“脾虚”腹泻大鼠的十二指肠和空肠处于运动亢进、推进加强的状态,这可能是大黄造型所出现的“脾虚失运”状态的机理之一。
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| 关 键 词： | 脾虚 电生理学 肌电描记术 肠 小 大鼠 |
Motility Changes of Small Intestinal Migrating Myoelectric Complex In Diarrhea Model Rats Produced by Penduliflory Elsholtzia |
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| Wen Jipu Wang Jianhua.Motility Changes of Small Intestinal Migrating Myoelectric Complex In Diarrhea Model Rats Produced by Penduliflory Elsholtzia[J].Journal of Guangzhou University of Traditional Chinese Medicine,1992(3). |
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| Authors: | Wen Jipu Wang Jianhua |
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| Institution: | Wen Jipu Wang Jianhua Department of Pi-wei Research |
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| Abstract: | Migrating Myoelectric Complex (MMC) were obtained from silver bipolar electrodes implanted in duodenum and jejunum of fasting rats respectively. The aim of our work was to determine the alterations of MMC in diarrhea model produced by decoction of Penduliflory Elsholtzia (PE). With oral injection of PE (8g/day) for 5 days, all model rats had the symptom of diarrhea. Meanwhile, phase 1 of MMC significantly decreased (in jejunum) or unchanged (in duodenum) while phase 2, phase 3 and cycle period of MMC significantly increased compared with the baseline recorded before the injections. Our results suggest that PE could strengthen the phasic contractile motility of small intestines in the rats. |
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| Keywords: | SPLEEN ASTHENIA ELECTROPKYSIOLOGY ELECTROMYOGRAPHY INTESTINE SMALL RATS |
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