老年冠心病合并糖尿病患者冠状动脉病变特点分析

目的:探讨老年冠心病合并糖尿病患者冠状动脉病变特点.方法:冠状动脉造影确诊为冠心病的老年(≥60岁)住院患者134例,其中合并2型糖尿病42例,未合并糖尿病92例,比较2组冠脉病变的特点及相关临床因素.结果:2组体质指数(BMI)、吸烟年限、高血压病史、血脂差异均无统计学意义(P＞0.05);2组冠脉病变狭窄程度及受累血管数及部位差异无统计学意义(P＞0.05),但合并糖尿病组病变数、末梢病变数较高(P＜0.05).多元逐步回归分析结果显示,老年患者冠脉病变狭窄程度的影响因素有低密度脂蛋白、年龄和吸烟年限;冠脉病变数、末梢病变数与糖尿病呈正相关.结论:老年冠心病合并糖尿病患者冠脉病变数多、末梢病变多.血脂代谢异常、吸烟合并糖尿病的老年患者更易发生冠脉病变.

Analyses of coronary artery lesion characteristics in aged patients with coronary artery disease and diabetes

Aim:To explore the characteristics of coronary artery lesion of aged patients with coronary disease and diabetes(DM).Methods:A total of 134 patients with coronary disease diagnosed by coronary artery angiography(CAG),aged more than 60 years,were allocated into 2 groups,including 42 cases complicated DM(DM group)and 92 case without DM(non-DM group).The coronary artery lesion characteristics and relevant clinical factors of the two groups were analyzed.Results:There were no statistical significance in BMI,smoking age,history of high blood pressure,and blood cholesterol between the two groups(P>0.05).There were no statistical significance in severity of coronary artery stenosis and the number of affected vessels between the two groups(P>0.05),but the number of pathological changes and number of curative effects were higher in the DM group(P<0.05).The factors affecting the severity of coronary artery stenosis were LDL level,age,and smoking age.Furthermore,the number of pathological changes in coronary artery and the curative effects were positively related to diabetes.Conclusion:Aged coronary disease patients with diabetes show more pathological changes in coronary artery and curative effects.Aged patients with abnormal lipid metabolism,smoking,and complication of diabetes maybe more likely to develop pathological changes in coronary artery.