催产素对新生儿高胆红素血症影响的临床观察

目的:观察产妇在分娩过程中应用催产素对新生儿高胆红素血症的影响.方法:选择320例足月健康新生儿,根据孕母产前是否使用催产素分为两组,观察组(使用催产素)108例,对照组(未使用催产素)212例,在出生后分别检测两组新生儿胆红素的水平及高胆红素血症发生率.结果:观察组胆红素的均值(287.73±41.27) μmol/L,明显高于对照组(184.73±62.70) μmol/L(u=17.58,P＜0.01),观察组高胆红素血症的发生率为38.89％,高于对照组的25.00％(X2=6.61,P＜0.05),差异均有统计学意义.结论:孕妇分娩时使用催产素可增加新生儿高胆红素血症的发生率,新生儿出生后应及早监测血清胆红素浓度.

The Clinical Effect Observation of Oxytocin on Neonatal Hyperbilirubinemia

Objective: To observe the effect of oxytocin applied to the lying-in women during childbirth on the neonatal hyperbilirubinemia.Methods:Together 320 full-term healthy newborns were divided into two groups according to maternal prenatal use of oxytocin,the observation group(using oxytocin) was 108 cases,and the control group(not using oxytocin) was 212 cases.All newborns’ bilirubin levels were detected to calculate the incidence of hyperbilirubinemia.Results: The mean bilirubin of the observation group(287.73±41.27) μmol/L was significantly higher than that of the control group(184.73±62.70) μmol/L(u=17.58,P<0.01).The incidence of hyperbilirubinemia of the observation group(38.89%) was also higher than that of the control group(25.00%),the difference was statistically significant(χ2=6.61,P<0.05).Conclusions: Application of oxytocin to lying-in women increased the incidence of neonatal hyperbilirubinemia.The newborn’s bilirubin level should be checked as soon as possible after birth.