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Immune Response to Haemophilus influenzae Type b Vaccination in Patients with Chronic Renal Failure
Authors:Nicole Hawdon   Eli B. Nix   Raymond S. W. Tsang   Garry Ferroni   William G. McCready   Marina Ulanova
Affiliation:aNorthern Ontario School of Medicine, Lakehead University, Thunder Bay, Ontario, Canada;bVaccine Preventable Bacterial Disease, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
Abstract:Adult chronic renal failure patients undergoing hemodialysis are at an increased risk of invasive Haemophilus influenzae type b (Hib) disease due to the lack of functionally active anti-Hib antibodies. The pediatric Hib polysaccharide-protein conjugate vaccine is highly immunogenic in these patients and can provide protection against invasive Hib infection for at least 1 year.
Keywords:
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