| 尿毒症患者透析前后外周血B细胞和T细胞及其亚群的研究 |
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| 引用本文： | 胡万如 刘淑佩. 尿毒症患者透析前后外周血B细胞和T细胞及其亚群的研究[J]. 标记免疫分析与临床, 1999, 6(1): 18-20 |
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| 作者姓名： | 胡万如 刘淑佩 |
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| 作者单位： | 江苏连云港市第一人民医院!连云港，222002，江苏连云港市第一人民医院!连云港，222002，江苏连云港市第一人民医院!连云港，222002 |
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| 摘 要： | 应用单克隆抗体技术检测了３５名正常人和３１例尿毒症患者外周血Ｂ细胞和Ｔ细胞亚群。结果显示：尿毒症患者外周血Ｂ细胞数显著地高于正常人（Ｐ〈０．００１），ＣＤ３、ＣＤ４低于正常人（Ｐ〈０．０１），ＣＤ４／ＣＤ８又非常显著地低于正常人（Ｐ〈０．００１）。因此认为，尿毒症患者为一种自身免疫调节异常的疾病。
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| 关 键 词： | 尿毒症 B细胞 T淋巴细胞亚群 血液透析 |
Study of B and T as well as T Subgroups of Lymphocytes in Peripheral Blood in Uremia |
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| Hu Wanru, Liu Shupei, He Haoming. Study of B and T as well as T Subgroups of Lymphocytes in Peripheral Blood in Uremia[J]. Labeled Immunoassays and Clinical Medicine, 1999, 6(1): 18-20 |
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| Authors: | Hu Wanru Liu Shupei He Haoming |
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| Abstract: | Using immunological technique to detect B and T as well as T subgroups of lymphocytes in pheripheral blood of patients with uremia, the results showed that the B lymphocyteswere extremely higher than those of normal people(P < 0. 001 ), but CD3, CD4 and the CD4/CD8were obviously lower (P < 0. 01 - P< 0. 001 ). The results indicate that uremia is a kind of selfimmunity disease with abnormal immunoregulation. Therefore, detecting B and T lymphocytes inuremia will be helpful in understanding the pathological mechanism of uremia and evaluation ofprognosis. |
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| Keywords: | Uremia B lymphocyte T lymphocyte subgroups |
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