肾移植术后肝功能损害的诊治

目的探讨肾移植术后肝功能损害的病因诊断及治疗。方法分析82例肾移植患者术后肝功能损害病因，提出合理而有效的治疗方案。结果82例肝功能损害患者中，药物毒性肝损害70例(85.5％)，全部治愈；乙肝病毒性肝损害12例(14.5％)，8例治愈，4例发生急性肝功能衰竭死亡。结论对肾移植术后肝功能损害，应仔细鉴别，区别的处理，应特别注意免疫抑制剂的调整和环孢素A浓度的监测。

Diagnose and Treatment of Liver Functional Lesion After Kidney Transplantation

Objective To investigate the etiological diagnosis and therapy of liver function lesion after kidney transplantation.Methods By analyzing the etiological factor of 82 cases of liver function lesion,we provided a reasonable and operative therapy scheme in kidney post-transplantation.Results Of 82 cases,the number of drug toxicity and viral hepatitis B which result in liver functional lesion were 70 cases(85 5%) and 12 cases(14 5%) respectively.The former were all cured,8 cases in the latter were cured and the other 4 cases were died from acute hepatic failure.Conclusions The liver function lesion of post-transplantation should be diagnosed carefully and treated particularly.Morever,the adjustment of immuno-suppressive drugs and monitoring circlosporin A concentration should be done for the patients with liver function damaged.