| 氨氯地平对肾性高血压及肾功能不全的疗效 |
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| 引用本文： | 陈红坤 郭志玲. 氨氯地平对肾性高血压及肾功能不全的疗效[J]. 中国新药与临床杂志, 1998, 17(3): 159-160 |
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| 作者姓名： | 陈红坤 郭志玲 |
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| 作者单位： | 洛阳医学高等专科学校附属医院 |
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| 摘 要： | 目的：观察氨氯地平治疗肾性高血压及保护肾功能的效果。方法：慢性肾脏疾病病人５０例（男性２９例，女性２１例，年龄４１±ｓ４ａ）用氨氯地平片５～１０ｍｇ，ｐｏ，ｑｄ，４ｗｋ为一个疗程。结果：降血压明显（Ｐ＜０．０１），２４ｈ尿蛋白量及血钾无变化，血肌酐下降（Ｐ＜０．０１），内生肌酐清除率上升（Ｐ＜０．０１）。结论：氨氯地平用于慢性肾脏疾病病人既可降低血压，也可以保护肾功能
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| 关 键 词： | 氨氯地平；肾性高血压；肾功能试验 |
Effects of amlodipine in treating renal hypertension and nephric dysfunction |
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| CHEN Hong_Kun,GUO Zhi_Ling,SONG Run_Luo. Effects of amlodipine in treating renal hypertension and nephric dysfunction[J]. Chinese Journal of New Drugs and Clinical Remedies, 1998, 17(3): 159-160 |
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| Authors: | CHEN Hong_Kun GUO Zhi_Ling SONG Run_Luo |
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| Abstract: | AIM: To observe the efficacy of amlodipine in treating renal hypertension and nephric dysfunction. METHODS: Fifty patients (M 29, F 21; age 41±s 4 a) with chronic renal diseases were treated with amlodipine 5_10 mg, po, qd for 4 wk. RESULTS: Amlodipine lowered blood pressure (P<0.01), but 24 h uroprotein and blood potassium showed no change. Blood creatinine decreased (P<0.01) and endogenous creatinine clearance increased (P<0.01). CONCULSION: Amlodipine not only lowers blood pressure, but also improves renal function in the patients with chronic renal diseases. |
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| Keywords: | amlodipine renal hypertension kidney function tests |
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