| 氟西汀治疗肠激惹综合征 |
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| 引用本文： | 张新琪,张增高,姜建波,刘京生. 氟西汀治疗肠激惹综合征[J]. 中国新药与临床杂志, 1998, 17(5): 289-290 |
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| 作者姓名： | 张新琪 张增高 姜建波 刘京生 |
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| 作者单位： | 青岛市第二卫生学校(张新琪)，青岛市胶州中心医院(张增高)，胶州市精神病医院(姜建波，刘京生) |
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| 摘 要： | 目的：观察氟西汀治疗肠激惹综合征的疗效。方法：治疗组５６例（男性１９例，女性３７例，年龄４３±ｓ１２ａ），给氟西汀２０ｍｇ，ｐｏ，ｔｉｄ；对照组５２例（男性１７例、女性２５例，年龄４２±１１ａ），给维生素Ｂ１２０ｍｇ、谷维素２０ｍｇ，ｐｏ，ｔｉｄ，对腹痛、腹泻较重者另加山莨菪碱１０ｍｇ，ｐｏ，ｔｉｄ。２组疗程均为４ｗｋ。观察治疗前后症状、大便次数及性状等。结果：治疗组总有效率９５％，比对照组总有效率５６％显著提高（Ｐ＜０．０１）。结论：氟西汀治疗肠激惹综合征有显著疗效。
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| 关 键 词： | 机能性结肠疾病；氟西汀；易激惹情绪 |
Fluoxetine in treatment of irritable bowel syndrome |
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| ZHANG Xin_Qi. Fluoxetine in treatment of irritable bowel syndrome[J]. Chinese Journal of New Drugs and Clinical Remedies, 1998, 17(5): 289-290 |
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| Authors: | ZHANG Xin_Qi |
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| Abstract: | AIM: To observe the effect of fluoxetine on irritable bowel syndrome. METHODS: Fifty-six patients (M 19, F 37; age 43±s 12 a) in treatment group received fluoxetine 20 mg, po, tid; 52 patients (M 17, F 25; age 42±11 a) in control group received vitamin B 1 20 mg and oryzanol 20 mg, po, tid. If epigastric pain and diarrhea were severe, anisodamine was added 10 mg, po, tid. The therapeutic course of the two groups was all 4 wk. The clinical symptoms of the patients and the time and character of the stools were observed before and after treatments. RESULTS: The total effective rate of the treatment group (95%) was superior to that of the control group (56%)(P<0.01). CONCLUSION: Fluoxetine in treating irritable bowel syndrome is effective. |
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| Keywords: | functional colonic disease fluoxetine irritable mood |
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