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Effects of Sleeve Gastrectomy and Medical Treatment for Obesity on Glucagon-like Peptide 1 Levels and Glucose Homeostasis in Non-diabetic Subjects
Authors:Juan Patricio Valderas  Veronica Irribarra  Lorena Rubio  Camilo Boza  Manuel Escalona  Yessica Liberona  Andrea Matamala  Alberto Maiz
Affiliation:(1) Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Catolica de Chile, Marcoleta 367, 6510260 Santiago, Chile;(2) Department of Digestive Surgery, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile;
Abstract:

Background  

The effects of medical and surgical treatments for obesity on glucose metabolism and glucagon-like peptide 1 (GLP-1) levels independent of weight loss remain unclear. This study aims to assess plasma glucose levels, insulin sensitivity and secretion, and GLP-1 levels before and after sleeve gastrectomy (SG) or medical treatment (MED) for obesity.
Keywords:
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