Mobilisation strategies for normal and malignant cells |
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| Authors: | To L Bik Levesque Jean-Pierre Herbert Kirsten E Winkler Ingrid G Bendall Linda J Hiwase Devendra K Antonenas Vicki Rice Alison M Gottlieb David Mills Anthony K Rasko John E J Larsen Stephen Beligaswatte Ashanka Nilsson Susan K Cooney Julian P Cambareri Antony C Lewis Ian D |
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| Affiliation: | Haematology, IMVS/SA Pathology and Royal Adelaide Hospital, Adelaide, Western Australia, Australia. bik.to@health.sa.gov.au |
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| Abstract: | This review evaluates the latest information on the mobilisation of haemopoietic stem cells for transplantation, with the focus on what is the current best practice and how new understanding of the bone marrow stem cell niche provides new insights into optimising mobilisation regimens. The review then looks at the mobilisation of mesenchymal stromal cells, immune cells as well as malignant cells and what clinical implications there are. |
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| Keywords: | ALC" },{" #name" :" keyword" ," $" :{" id" :" kw0115" }," $$" :[{" #name" :" text" ," _" :" absolute lymphocyte count ALL" },{" #name" :" keyword" ," $" :{" id" :" kw8115" }," $$" :[{" #name" :" text" ," _" :" acute lymphoid leukaemia AML" },{" #name" :" keyword" ," $" :{" id" :" kw8195" }," $$" :[{" #name" :" text" ," _" :" acute myeloid leukaemia CLL" },{" #name" :" keyword" ," $" :{" id" :" kw8225" }," $$" :[{" #name" :" text" ," _" :" chronic lymphocytic leukaemia G-CSF" },{" #name" :" keyword" ," $" :{" id" :" kw8855" }," $$" :[{" #name" :" text" ," _" :" granulocyte colony-stimulating factor GM-CSF" },{" #name" :" keyword" ," $" :{" id" :" kw8365" }," $$" :[{" #name" :" text" ," _" :" granulocyte-macrophage colony-stimulating factor GVHD" },{" #name" :" keyword" ," $" :{" id" :" kw9115" }," $$" :[{" #name" :" text" ," _" :" graft versus host disease HGF" },{" #name" :" keyword" ," $" :{" id" :" kw2115" }," $$" :[{" #name" :" text" ," _" :" haemopoietic growth factor HSCs" },{" #name" :" keyword" ," $" :{" id" :" kw3115" }," $$" :[{" #name" :" text" ," _" :" haemopoietic stem/progenitor cells MGDF" },{" #name" :" keyword" ," $" :{" id" :" kw4115" }," $$" :[{" #name" :" text" ," _" :" megakaryocyte growth and development factor OS" },{" #name" :" keyword" ," $" :{" id" :" kw5115" }," $$" :[{" #name" :" text" ," _" :" overall survival PFS" },{" #name" :" keyword" ," $" :{" id" :" kw6115" }," $$" :[{" #name" :" text" ," _" :" progression free survival SCF" },{" #name" :" keyword" ," $" :{" id" :" kw5565" }," $$" :[{" #name" :" text" ," _" :" stem cell factor Haemopoietic stem cells immune cells leukaemic cells mobilisation |
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