葡立胶囊与玻璃酸钠关节内注射治疗膝关节骨关节炎疗效分析 |
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引用本文: | 吴侗,刘建. 葡立胶囊与玻璃酸钠关节内注射治疗膝关节骨关节炎疗效分析[J]. 泸州医学院学报, 2009, 32(2): 156-158 |
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作者姓名: | 吴侗 刘建 |
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作者单位: | 四川省人民医院风湿免疫科,四川成都,610072 |
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摘 要: | 目的:对比葡立胶囊与玻璃酸钠关节内注射治疗膝关节骨关节炎(oA)的疗效。方法:纳入120例膝关节OA的患者,分为2组,A组采用玻璃酸钠膝关节腔内注射,1次/周,5次为一个疗程,B组采用葡立胶囊口服。结果:根据Western Ontario MacMaster(WOMAC)评分对疼痛、僵硬、身体功能等疗效观察指标进行评估,两组均能改善上述症状,而A组在疼痛与关节活动度改善疗效均优于B组,两组疗效间有显著性差异(P〈0.05)。结论:玻璃酸钠关节内注射与葡立胶囊对膝骨关节炎的治疗确有疗效,玻璃酸钠在疗效上优于葡立胶囊。
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关 键 词: | 玻璃酸钠 葡立胶囊 骨关节炎 膝关节 关节内注射 |
ANALYSIS OF THE THERAPEUTIC EFFECT OF GLUCOSAMINE HYDROCHLORIDE AND SODIUM HYALURONATE ON KNEE OSTEOARTHRITIS |
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Affiliation: | Wu tong,et al |
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Abstract: | Objective:To compare the efficacy of glucosamine hydrochloride capsules and sodium hyaluronate on knee osteoarthritis (OA). Methods:One hundred and twenty patients with knee osteoarthritis were divided into 2 groups: Group A intraarticular sodium hyaluronate once a week for 5 weeks, and group B using glucosamine hydrochloride capsules.Results:Assessed by the Western Ontario MacMaster(WOMAC)scoring method,symptoms of pain , stiff and daily activites were improved in both groups , but the therapeutic efficacy was significantly betterin group A (P〈0.05) , not only on the pain relief but also on the knee joint activity. Conclusion:The i,traarticular injection of sodium hyaluronate for OA has better outcome than the glueosamine hydrochloride capsules. |
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Keywords: | Sodium hyaluronate Hlucosamine hydrochloride capsules Osteoarthritis Knee Intraartieular injection |
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