中药治疗COPD稳定期肺肾阴虚型患者的临床疗效及对肺功能的影响

目的： 探讨中药治疗慢性阻塞性肺疾病（COPD）稳定期肺肾阴虚型患者的临床疗效及对肺功能影响。 方法： 将138例COPD稳定期肺肾阴虚患者随机分入对照组与治疗组，对照组患者接受常规西医治疗措施，治疗组患者在对照组治疗基础上加用补肺益阳化痰中药颗粒口服，疗程2个月。比较两组临床疗效、肺功能及生活质量的差别。 结果： 治疗组治疗总有效率显著高于对照组，差别具有统计学意义（95.7% vs 82.4%，P<0.05）；治疗后治疗组肺功能指标用力肺活量（FVC）、第1秒用力肺活量占预计值百分比（FEV₁）及FEV₁/FVC显著优于对照组（P<0.05）；治疗组健康状况调查问卷（SF-36）评分显著高于对照组（P<0.05）。 结论： 补肺益阳化痰中药可显著提高COPD稳定期肺肾阴虚患者临床疗效，并改善肺功能。

Effect of Chinese Medicine in Treatment of Stable COPD Patients and Influence for Lung Function

Objective: To explore the effect of Chinese medicine in treatment of stable chronic obstructive pulmonary disease(COPD) patients and the influence for lung function. Method: One hundred and thirty-eight cases with stable COPD were randomly divided into control group and experience group. Control group received routine western medicine therapy and experience group were given Bufei Yiyang Huatan granules treatment. The course of treatment was 2 months. Clinical effect, lung functions and life quality were compared between two groups. Result: The effective rates of treatment in experience group was much higher than that in control group (95.7% vs 82.4%, P<0.05);after treatment, FVC, FEV₁ and FEV₁/FVC in experience group were superior to control group (P<0.05);comparison with control group, SF scores in experience group greatly increased (P<0.05). Conclusion: Bufei Yiyang Huatan granules for stable COPD patients greatly improve the clinical effect and lung functions.