声诺维超声造影评价碘油过敏不孕妇女输卵管通畅性的临床价值

目的 探讨声诺维（SonoVue）超声造影评价输卵管通畅性的临床应用价值.方法 选择对碘油过敏不孕妇女35例,采用声诺维作为造影剂,在低机械指数实时谐波声学造影条件下,经腹部超声引导行子宫输卵管超声造影（HyCoSy）,观察输卵管显影情况,评价输卵管的畅通性,并与腹腔镜下输卵管通染液术的结果进行对照比较.结果 子宫输卵管超声造影与腹腔镜下输卵管通染液术的结果比较,差异无统计学意义（P＞0.05）.两种检查方法一致性较好（Kappa值=0.933）.子宫输卵管超声造影的灵敏度为97.9％、特异度为95.5％、正确诊断指数为93.4％.结论 子宫输卵管超声造影可实时、动态、多切面观察输卵管通畅情况,是一种评价不孕症患者输卵管通畅性的有效方法,尤其适合碘油过敏者.

Clinical value of Sono Vue contrast-enhanced ultrasonography in the evaluation of fallopian tube patency for infertile women allergic to iodized oil

Objective To evaluate the clinical value of SonoVue contrast-enhanced ultrasonography in the evaluation of fallopian tube patency for infertile women allergic to iodized oil.Methods Using real-time harmonic contrast imaging with low mechanical index hysterosalpingogram,35 infertile women who are allergic to iodized oil underwent contrast-enhanced ultrasonography with SonoVue contrast agent.Through transabdominal hysterosalpingo-contrast-ultrasonography （HyCoSy）,fallopian tube development situation was observed,fallopian tube patency was evaluated.The results were compared with that of laparoscopic dye perturbation.Results The results of HyCoSy and laparoscopic dye pertubation showed no statistically significant difference （P〉0.05）.The accordance of the two methods was good,with the Kappa value of 0.933.The sensitivity and specificity of HyCoSy were 97.9% and 95.5%,respectively,and the correct diagnosis rate was 93.4%.Conclusion The hysterosalpingo-contrast-ultrasonography could show the multi-slice,real-time and dynamic situation of fallopian tube,which is an effective method to evaluate the fallopian tube patency of infertile patients,especially for those with oil iodine allergy.