匹多莫德治疗婴幼儿复发性鹅口疮的疗效观察

目的 观察匹多莫德对婴幼儿复发性鹅口疮的疗效.方法 选取66例复发性鹅口疮患儿,随机分为观察组和对照组各33例,对照组予2.5％碳酸氢钠清洁口腔后,制霉菌素混悬液涂抹口腔内黏膜;观察组在对照组的基础上加用匹多莫德口服治疗.治疗6d后观察两组疗效,1个月后再比较两组的复发率.结果 观察组总有效率为96.9％,高于对照组的81.8％（P＜0.05）,复发率3％低于对照组的21.2％,差异有统计学意义（P＜0.05）.结论 匹多莫德有效治疗婴幼儿鹅口疮,并降低复发率.

Clinical effect of Pidotimod in the treatment of infants with recurrent thrush

Objective To analyze the clinical effect of Pidotimod in the treatment of infants with recurrent thrush.Methods Sixty-six infants with recurrent thrush were randomly divided into two groups,with 33 patients in group A and 33 patients in group B.Group B applied 2.5% sodium bicarbonate solution of oral care,oral nystatin suspension smear.Group A used the additional treatment of Pidotimod based on the group B.The clinical effect of two groups were compared six days after treatment,and the recurrence rates were compared 1 month after treatment.Results The total effective rate was 96.9% in group A,significantly higher than 81.8% in group B.The recurrence rate was 3% in group A,significantly lower than 21.2% in group B.Statistical analysis showed significant differences between the two groups （P〈0.05）.Conclusion Pidotimod can treat infants with recurrent thrush effectively and reduce the recurrence rate.