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齐拉西酮对慢性精神分裂症患者生活质量影响的临床研究
引用本文:熊建文,杨远坚,周朝雄,周宇鹏. 齐拉西酮对慢性精神分裂症患者生活质量影响的临床研究[J]. 中国医药指南, 2014, 0(24): 14-15
作者姓名:熊建文  杨远坚  周朝雄  周宇鹏
作者单位:江西省精神病医院,江西南昌330029
摘    要:目的探讨齐拉西酮对慢性精神分裂症患者生活质量的影响。方法将使用传统抗精神病药进行维持治疗的慢性精神分裂症门诊患者30例换用新型抗精神病药齐拉西酮治疗6个月。采用阳性与阴性症状量表(PANSS)、不良反应量表(TESS)、精神分裂症患者生活质量量表(SQLs)及社会功能缺陷筛选表(SDSS)分别评定换用齐拉西酮治疗前后患者的疗效、不良反应及生活质量情况。结果换用齐拉西酮治疗6月后,PANSS中阴性症状、TESS、SQLs、SDSS评分均显著下降。结论齐拉西酮能显著改善慢性精神分裂症患者的生活质量。

关 键 词:齐拉西酮  慢性精神分裂症  生活质量

A Clinical Study of the Influence of Ziprasidone on the Quality of Life in Patients with Chronic Schizophrenia
XIONG Jian-wen,YANG Yuan-jian,ZHOU Chao-xiong,ZHOU Yu-peng. A Clinical Study of the Influence of Ziprasidone on the Quality of Life in Patients with Chronic Schizophrenia[J]. Guide of China Medicine, 2014, 0(24): 14-15
Authors:XIONG Jian-wen  YANG Yuan-jian  ZHOU Chao-xiong  ZHOU Yu-peng
Affiliation:(Jiangxi Mental Hospital, Nanchang 330029, China)
Abstract:Objective To explore the treatment effects of ziprasidone on the quality of life in chronic schizophrenia patients. Methods 30 cases of chronic schizophrenic outpatient in maintenance treatment period were recruited in present study. Ziprasidone were used to substitute the traditional antipsychotics for six months, and the positive and negative symptom scale (PANSS),the treatment emergent symptom scale(TESS), the schizophrenia quality of life scale (SQLS)and the social disability screening schedule(SDSS)were used to evaluate efficacy, side effects and quality of life. Results After the treatment for six months, all the scores of PANSS-negative symptom scale, TESS, SQLS and SDSS were significant decreased. Conclusion Ziprasidone can improve the quality of life of chronic schizophrenic patients.
Keywords:Ziprasidone  Chronic schizophrenia  The quality of life
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