Abstract: | Ultrastructural analysis showed differences in the response of the epithelium of the proximal and distal portions of the nephron during postmortem survival of the kidney and its experimental ischemia in noninbred albino rats. During autolysis of the organ in the cadaver intracellular edema develops in the tubular epithelium and characteristic changes appear in the ultrastructure of the mitochondria. Under the conditions of experimental ischemia, marked changes in the lysosomal system of the cells, swelling of the mitochondria, and considerable dilatation of the cisterns of the endoplasmic reticulum and the Golgi lamellar complex take place against the background of intracellular edema.Labortory of Electron Microscopy, Central Research Laboratory, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR Yu. M. Lopukhin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 79, No. 3, pp. 118–121, March, 1975. |