The value of anti-rods and rings antibodies in Western China population: A retrospective study |
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| Authors: | Lei Zhang Jianzhao Zhai Lu Wang Zhuochun Huang Jing Hu Lixin Li Junlong Zhang Honghu Tang Min Yang Yongkang Wu |
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| Institution: | 1. Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China;2. Department of Rheumatology, West China Hospital, Sichuan University, Chengdu, China |
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| Abstract: | The study aimed to retrospectively investigate the clinical significance of anti-rods and rings (anti-RR) antibodies in antinuclear antibodies (ANAs) test samples of western China. Between January 2016 and November 2018, the laboratory data and clinical details of patients with positive anti-RR antibodies were collected and analysed. The results showed that total of 197 227 patients tested, 109 453 patients presented with positive ANAs (55.50%), but only 107 patients with positive anti-RR antibodies (0.10%), including 51 females and 56 males. Diagnose were established in 51 of 107 patients: 25 were hepatopathy (HCV 8/25, HBV 12/25); 13 were autoimmune diseases (AID); and 7 were renal insufficiency; 6 were chronic obstructive pulmonary disease (COPD). We make the conclusions that anti-RR antibodies have a low prevalence, and there is no gender difference. Anti-RR antibodies exist other diseases besides hepatitis C, such as HBV, some autoimmune diseases, renal insufficiency and COPD, which we need further investigation. |
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| Keywords: | antinuclear antibodies anti-rods and rings antibodies hepatitis B hepatitis C hepatopathy |
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