酵母重组胶原蛋白液体敷料在面部敏感性皮肤中的应用效果

目的 探究酵母重组胶原蛋白液体敷料应用于面部敏感性皮肤的临床效果。方法 选取2020年3月-12月我院收治的206例因皮炎、湿疹等引起面部敏感性皮肤患者作为研究对象,采用随机数字表法分为对照组（n=98）和试验组（n=108）,对照组采用透明质酸钠凝胶冷敷治疗,试验组采用酵母重组胶原蛋白液体敷料冷喷治疗。比较两组治疗前后主客观症状体征评分变化、临床疗效及不良反应发生率。结果 两组治疗后各项主观症状评分均低于治疗前,且试验组低于对照组,差异有统计学意义（P＜0.05）;两组治疗后客观体征各项评分低于治疗前,且试验组低于对照组,差异有统计学意义（P＜0.05）;两组治疗总有效率比较,差异无统计学意义（P＞0.05）;两组随访期间均未出现不良反应。结论 酵母重组胶原蛋白液体敷料应用于面部敏感性皮肤效果确切,能够有效缓解患者症状,且安全性良好。

Application Effect of Yeast Recombinant Collagen Liquid Dressing in Facial Sensitive Skin

Objective To explore the clinical effect of yeast recombinant collagen liquid dressing on facial sensitive skin. Methods A total of 206 patients with facial sensitive skin caused by dermatitis and eczema admitted to our hospital from March to December 2020 were selected as the research objects. They were divided into control group (n=98) and experimental group (n=108) by random number table method. The control group was treated with cold compress of sodium hyaluronate gel, and the experimental group was treated with cold spray of yeast recombinant collagen liquid dressing. The changes of subjective and objective symptoms and signs scores, clinical efficacy and incidence of adverse reactions were compared between the two groups before and after treatment. Results After treatment, the subjective symptom scores of the two groups after treatment were lower than those before treatment, and those in the experimental group were lower than those in the control group, the difference was statistically significant (P<0.05). After treatment, the scores of objective signs in the two groups were lower than those before treatment, and those in the experimental group were lower than the control group, the differences were statistically significant (P<0.05). There was no significant difference in the total effective rate between the two groups (P>0.05). No adverse reactions occurred in the two groups during the follow-up period. Conclusion Yeast recombinant collagen liquid dressing is effective in facial sensitive skin, which can effectively relieve the symptoms of patients, and has good safety