慢性肝炎及肝硬化患者血钙浓度的分析

目的:观察慢性肝炎与肝硬化患者血钙浓度变化,以及肝硬化Child-pugh分级与血钙浓度关系。方法:对190例慢性肝炎及肝硬化患者做血钙浓度测定,同时设正常对照组90例。结果:在本组研究中,正常对照组、慢性肝炎组血钙浓度均值相近(P>0.05),肝硬化组血钙浓度均值(1.94±0.22)mmol/L明显低于肝炎组。血钙浓度<2.03mmol/L者,慢性肝炎组30.4%,肝硬化组73.5%,两组比较有显著性差异(P<0.01)。随着Child-pugh积分的增高,肝硬化程度加重,血钙浓度逐渐降低,A、B、C级之间比较有显著性差异(P<0.01)。结论:血钙浓度可作为判断肝炎与肝硬化肝功能减退的重要指标。

Analysis of Blood Calcium Level in Patients with Chronic Hepatitis and Cirrhosis

Objective: To observe the variation of blood calcium level in patients with chronic hepatitis and the relation between cirrhosis Childpugh classification and blood calcium level.Methods: The levels of blood calcium in 190 patients with chronic hepatitis and cirrhosis were tested.A normal control group with 90 cases was set.Results: The levels of blood calcium in control group and hepatitis group were similar(P>0.05),while the calcium level in cirrhosis group(1.94±0.22) was lower than that in hepatitis group obviously.There were 30.4% patients in hepatitis group and 73.5% in cirrhosis group with a blood calcium level less than 2.03mmol/L.There was a significant difference between them(P<0.01).With Child-pugh integral increasing,cirrhosis degree aggravated and the level of blood calcium depressed gradually.The difference among the A,B and C degree was significant(P<0.01). Conclusions: The level of blood calcium is the important index for judging liver debility in patients with chronic hepatitis and cirrhosis.