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Cell aging in vitro: a historical perspective
Authors:J A Witkowksi
Affiliation:Imperial Cancer Research Fund Laboratories, St. Bartholomew's Hospital, London.
Abstract:This article describes the historical background to the demonstration by Hayflick and Moorhead that human diploid cell strains in culture have limited life-spans. I suggest that the recognition of cell aging in vitro is an example from the biological sciences of a Kuhnian scientific revolution.
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