| 毛茛注射液痛点注射治疗骨质增生性疼痛1058例 |
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| 引用本文： | 陈孔奇,赵毅虹.毛茛注射液痛点注射治疗骨质增生性疼痛1058例[J].中国新药与临床杂志,1994(3). |
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| 作者姓名： | 陈孔奇 赵毅虹 |
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| 作者单位： | 湖南省财贸医院 |
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| 基金项目： | 湖南省科学技术委员会资助,长沙市科学技术委员会资助 |
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| 摘 要： | 毛茛注射液（１ｍＬ含生药干品１ｇ）经药效研究及动物和临床试验表明具有明显镇痛、抗炎和改善微循环作用，而无毒性及糖皮质激素类药的不良反应。用该制剂痛点注射治疗骨质增生性疼痛１０５８例（男性４７６例，女性５８２例；年龄４８±ｓ１０ａ；病程３．０±１．０ａ）。每点注药０．１－２ｍＬ，总量不超过６ｍＬ，每天或隔天１次。治疗２８±５次。总有效率９８．３０％。除女性患者有月经不正常外，无其他不良反应。
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| 关 键 词： | 中草药，毛茛，骨关节炎，疼痛，病灶内注射 |
Treatment of osteoarthritis with Ranunculus japonicus extract injection to pain-point in 1058 patients |
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| CHEN Kong-Qi,ZHAO Yi-Hong.Treatment of osteoarthritis with Ranunculus japonicus extract injection to pain-point in 1058 patients[J].Chinese Journal of New Drugs and Clinical Remedies,1994(3). |
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| Authors: | CHEN Kong-Qi ZHAO Yi-Hong |
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| Abstract: | Pharmacological and clinical studies proved Ranunculus japonicus extract had obvious analgesic,antiinflammatory effect with improvement of microcirculation,but without toxicity and adverse reaction caused by glucocorticoids.1058 patients of osteoarthritis(M476,F 582;age 48±s 10 a;course of disease 3.0±1.0a)received injection of Ranunculusjaponicus extract(lg dried plant/mL)0.1-2mL at each point,total dose less than 6 mL,qd or qod for 28±5 times.Results showed that the total response rate was 98.30%,Only 21 female patients experienced menstruation disorders.It is a promising drug in treating osteoarthritis. |
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| Keywords: | Chinese herbal drugs Ranunculus japonicus osteoarthritis pain intralesional injections |
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