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Paraneoplastic production of granulocyte colony-stimulating factor in a bladder carcinoma
Authors:Turalic Haris  Deamant Frank D  Reese Jeffrey H
Affiliation:Department of Medicine, Weiler Hospital of the Albert Einstein College of Medicine, Bronx, New York, USA.
Abstract:We report the case of a 51-year-old female with poorly differentiated bladder carcinoma who presented with leukocytosis and hypercalcemia. Granulocyte colony-stimulating factor was noted to be twice the normal level. Paraneoplastic leukocytosis in bladder carcinoma is rare, is often associated with paraneoplastic hypercalcemia, and appears to represent a particularly aggressive form of the disease.
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