甲磺酸罗哌卡因用于臂丛神经阻滞效果观察

目的：评价甲磺酸罗哌卡因用于臂丛神经阻滞的临床效果和安全性，并与0．25％的布比卡因进行比较。方法：ASA分级Ⅰ～Ⅱ级60例拟行前臂手术患者，随机分为两组：A组（0．3％甲磺酸罗哌卡因）和B组（0．25％布比卡因）。术中连续监测BP、HR、SpO2，观察感觉神经阻滞起效时间．运动神经阻滞起效时间，感觉和运动神经阻滞作用时间，不良反应及术后并发症。结果：A组与B组感觉阻滞起效时间、感觉阻滞作用时间及运动阻滞起效时间相似（P〉0．05）；但运动阻滞作用时间A组长于B组（P〈0．05）。两组SBP、HR和SpO2与麻醉前相比差异无统计学意义。结论：0．3％甲磺酸罗哌卡因臂丛麻醉用于前臂手术安全有效，和0．25％的布比卡因相比，感觉和运动阻滞起效时间相似．但运动阻滞持续时间长。

Effective observation of ropivacaine mesyfate in brachial plexus block

Objective：To evaluate the clinical efficacy and the security of ropivacaine mesylate versus 0.25% bupivacaine in brachial plexus block in the patients undergoing forearm surgery. Methods ：Sixty ASA Ⅰ and II patients were randomly designed to receive 0.3% ropivacaine mesylate （group A,n=30） and 0.25%bupivacaine （group B,n=30）. BP, HR,SpO2, onset time of sensory nerve block and motor block,duration of sensory nerve block and motor btock, adverse reaction and post-operative complications were observed and compared.Results：There were no differences between the groups with onset time of sensory nerve block and motor block, duration of sensory nerve block （P〉0.05）.The duration of motor block in group A was longer than that in group B （P〈0.05）.No significant differences were found in SBP,HR and SpO2 in both groups compared with those before anesthesia.Conclusion：0.3% ropivacaine mesylate is safe and efficacious when used in brachial plexus block in the patients undergoing forearm surgery.Compared with 0.25% bupivacaine,there were no significant differences in onset time of sensory nerve block and motor block,but the motor block of 0.3%ropivacaine lasted longer.