脂联素在妊娠期糖尿病患者中的表达 |
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引用本文: | 朱高红,段炼,王炳坤,杨坚.脂联素在妊娠期糖尿病患者中的表达[J].昆明医学院学报,2007,28(2B):13-16. |
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作者姓名: | 朱高红 段炼 王炳坤 杨坚 |
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作者单位: | [1]昆明医学院第一附属医院,云南昆明650032 [2]昆明鹤庆县人民医院,云南大理671500 |
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摘 要: | 目的探讨脂联素与妊娠期糖尿病(GDM)的关系,方法妊娠期糖尿病患者、2型糖尿病患者及正常对照组各40例,采用体外放射免疫分析方法检测其血浆脂联素、血糖及胰岛素水平,同时测身高、体重,计算体重指数(BMI)和胰岛素抵抗性(HOMA-IR).结果血浆脂联素(APN)浓度在GDM组、T2DM组明显低于对照组,有显著性的差异,结论脂联素可用来筛查GIGT和GDM患者。
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关 键 词: | 脂联素 妊娠期糖尿病 表达 |
文章编号: | 1003-4706(2007)2B-0013-03 |
修稿时间: | 2007-01-12 |
The Expression of Adiponectin in Patients with Gestational Diabetes Mellitus |
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Abstract: | Objective To observe the expression change of the serum adiponectin levels of patients with the gestational diabetes mellitus so as to examine whether there exerts a relationship between them and diabetes. Methods RIA was used to examine adiponectin in 40 patients for each group. Meanwhile plasma levels of insu-lin, glucose, height, weigh, body mass index and HOMA-IR were measured and calculated. Results The mean concentration of adiponectin in serum from the gestational diabetes mellitus and type 2 diabetic patients were significantly lower than that in control group. Conclusion Adiponectin will play an important role in moni-tor the patients of GIGT and GDM. |
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Keywords: | Adiponectin Gestational diabetes mellitus Expression |
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