| 铝对体外培养小鼠卵母细胞减数分裂的影响 |
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| 引用本文： | 沈维干,李朝军.铝对体外培养小鼠卵母细胞减数分裂的影响[J].卫生研究,1999,28(5):267-268. |
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| 作者姓名： | 沈维干 李朝军 |
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| 作者单位： | 扬州大学医学院!扬州225001 |
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| 摘 要： | 本实验采用小鼠卵母细胞体外培养的方法研究了３～６０ｍ ｇ／ Ｌ 的硝酸铝对小鼠卵母细胞减数分裂的影响。结果表明，铝对卵母细胞生发泡破裂（ Ｇ Ｖ Ｂ Ｄ）没有影响，但可以抑制卵母细胞第一极体的排出，３０ｍ ｇ／ Ｌ和 ６０ｍ ｇ／ Ｌ的两个剂量组可降低卵母细胞的存活率。实验结果提示铝对小鼠卵母细胞的减数分裂有破坏作用。
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| 关 键 词： | 铝 卵母细胞 小鼠 |
Effect of aluminium on meiotic maturation of mouse oocyte in vitro] |
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| Shen Weigan,Ji Quanlan,Li Chaojun,Chen Yan,et al..Effect of aluminium on meiotic maturation of mouse oocyte in vitro][J].Journal of Hygiene Research,1999,28(5):267-268. |
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| Authors: | Shen Weigan Ji Quanlan Li Chaojun Chen Yan |
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| Institution: | Medical College of Yangzhou University, Yangzhou 225001, China. |
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| Abstract: | The effect of aluminium nitrate on the meiotic maturation of mouse oocyte was studied in the culture of mouse oocyte. The results showed that aluminium nitrate could inhibite the extruding of the first polar body and the dose of 30mg/L and 60 mg/L could affect the viability of mouse oocyte, but little impact on the germinal vesicle breakdown(GVBD) of oocyte. The results indicated that aluminium nitrate might be hazardous to the meiotic maturation of mouse oocyte. |
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| Keywords: | aluminium oocyte mouse |
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