| 260例乙型肝炎病毒感染孕妇母婴垂直传播中相关因素 |
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| 引用本文： | 陈文芹,单颖,顾琴,曾雪芹,汪洁云,樊珏,安晓霞,龚波. 260例乙型肝炎病毒感染孕妇母婴垂直传播中相关因素[J]. 中国妇幼保健, 2011, 26(23): 3541-3542 |
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| 作者姓名： | 陈文芹 单颖 顾琴 曾雪芹 汪洁云 樊珏 安晓霞 龚波 |
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| 作者单位： | 上海市长宁区妇幼保健院,200051 |
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| 基金项目： | 上海市长宁妇幼保健院科研基金赞助〔Y2010-11〕 |
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| 摘 要： | 目的:探讨乙型肝炎病毒(HBV)感染孕妇在母婴垂直传播中的相关因素。方法:对孕10个月分娩的260例HBV感染孕妇的资料进行回顾性分析,观察新生儿脐血的HBVM模式及其与母亲模式的关系。采用化学发光法对产前孕妇进行HBVM免疫学标志联合测定,分娩后新生儿取脐血检测HBVM免疫学测定。结果:①乙肝表面抗原(HBsAg)阳性母亲的新生儿脐血HBsAg(和或HBeAg)阳性率34.23%(89/260),其中58例大三阳者新生儿脐血HBsAg(和或HBeAg)阳性率高达82.76%(48/58),202例小三阳者新生儿脐血HBsAg(和或HBeAg)阳性率达20.30%(41/202)。②89例新生儿感染者中,阴道顺产者有44例,剖宫产者有45例。③新生儿所出现的抗体阳性结果几乎都是其母亲所具有的抗体阳性结果。结论:HBeAg阳性是母婴垂直传播HBV的重要因素,剖宫产并不能降低HBsAg阳性母亲的新生儿脐血HBsAg(或HBeAg)阳性率。新生儿体内的抗体几乎全部来自于母体。
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| 关 键 词： | 乙型肝炎病毒 乙型肝炎病毒标志物 垂直传播 |
Related factors of mother-to-child vertical transmission in 260 pregnant women with hepatitis B virus infection |
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| CHEN Wen-Qin,SHAN Ying,GU Qin et al.Maternal , Child Health Hospital of Changning District,Shanghai ,China. Related factors of mother-to-child vertical transmission in 260 pregnant women with hepatitis B virus infection[J]. Maternal and Child Health Care of China, 2011, 26(23): 3541-3542 |
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| Authors: | CHEN Wen-Qin SHAN Ying GU Qin et al.Maternal Child Health Hospital of Changning District Shanghai China |
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| Affiliation: | CHEN Wen-Qin,SHAN Ying,GU Qin et al.Maternal and Child Health Hospital of Changning District,Shanghai 200051,China |
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| Abstract: | Objective:To explore the related factors of mother-to-child vertical transmission in pregnant women with hepatitis B virus(HBV) infection.Methods:The data of 260 pregnant women with HBV infection were analyzed retrospectively,the relationship between HBV markers in umbilical blood of neonates and their mothers was observed.Chemical luminescence method was used to detect HBV markers before pregnancy,then the HBV markers in umbilical blood of neonates after birth were detect by immunological method.Results:Th... |
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| Keywords: | Hepatitis B virus Hepatitis B virus marker Vertical transmission |
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