孕中期产前筛查在优生优育中的重要性

目的对孕妇血清甲胎蛋白AFP、游离绒毛膜促性腺激素β—HCG用于唐氏综合征、18-三体和神经管畸形筛查进行回顾性分析，探讨产前筛查在优生优育中的重要意义。方法对2009年11月至2010年12月我院国产保健门诊单胎孕妇2969例妊娠中期（15周-20^＋6周），采用时间分辨法检测AFP、Free—β-HCG，对筛查高风险者转诊，诊断机构作产前诊断确诊。结果2969例中筛出3例异常，经确诊其中1例为腹璧裂，1例为神经管缺陷，1例为染色体异常。结论孕妇清标记物筛查能有效降低需要进行创伤性产前诊断的孕妇比例，降低染色体痰病患儿出生几率，提高出生人口素质。

The value of prenatal screening in the middle pregnant women

Objective maternal serum alpha- fetoprotein AFP, human ehorionie gormdotropin flee β - HCG for Down＇ s syndrome, 18 - Three - body screening and neural tube defects were reviewed retrospectively to explore the establishment of normal capacity in the region before the screening risk value. Methods from 2009 to 2010 in our hospital outpatient perinatal care of pregnant women 2969 cases of singleton pregnancies trimester （15 weeks to 22 ＋ 6 weeks）, using time - resolved detection AFP, Free -β - HCG, on the screening of high risk referral agency for the prenatal diagnosis of confirmed diagnosis. Results 2969 eases out of 3 cases of abnormal screening CPC, of which 1 case was diagnosed by abdominal deft, a neural tube defect, and 1 sex chromosome abnormalities. Conclusion Detection of maternal serum marker screening can reduce the need for invasive prenatal diagnosis of the proportion of pregnant women and reduce the risk of chromosomal disorders in children born to improve the quality of newborn babies.